Hot Selling Purity Powder Form CAS 65277-42-1 Ketoconazole 99% in Stock

• CAS No.: 65277-42-1
• Formula: C26h28cl2n4o4
• EINECS: 265-667-4
• Grade: Pharma
• Molecular Formula: C26h28cl2n4o4
• Appearance: White Powder
• Model NO.: LDKJ01-348
• Storage: Cool Dry Place
• Shelf Life: 2 Years
• Transport Package: 25kg Carton Drum (32cm*58cm)or 1kg Foil Bag (10cm*
• Specification: 1kg/bag
• Trademark: Lingding
• Origin: Hebei, China
• Production Capacity: 8000kilogram/Per Month

Product Description

Product Description

Product Name:	Ketoconazole
CAS:	65277-42-1
MF:	C26H28Cl2N4O4
MW:	531.43
EINECS:	265-667-4

Ketoconazole is a synthetic imidaz antifungal drug used primarily to treat fungal infections. Ketoconazole is sold commercially as a tablet for oral administration (although this use has been discontinued in a number of countries), and in a variety of formulations for topical administration, such as creams (used to treat tinea; cutaneous candidiasis, including candidal paronychia; and pityriasis versicolor) and shampoos (used primarily to treat dandruff-seborrhoeic dermatitis of the scalp).
Ketoconazole is used to treat certain serious fungal infections in the body. Ketoconazole belongs to the class of drugs called azol antifungals. It works by stopping the growth of the fungus.

Application:
Pharmacology: ketoconazole belongs to azol-class antifungal drugs and has antifungal activity against various kinds of genus of deep fungal infections such as Candida, Fonsecaea, Coccidioides, Histoplasma, Sporothrix spp as well as Trichophyton. However, this product has a relative weak activity against Aspergillus, Sporothrix schenckii as well as some species of Dermateaceae and Mucor. This product, through actively interfering with the activity of cytochrome P-450, is capable of inhibiting the biosynthesis of the major steroids - ergosterol of the fungal cell membrane. Therefore, it destroys the fungal cell membrane and changes its permeability, resulting in the leakage of important intracellular material. Ketoconazole can also inhibit the biosynthesis of fungal triglyceride and phospholipid biosynthesis, inhibit the activity of oxidase and peroxidase, causing accumulation of intracellular hydrog peroxid which further leads to cell submicroscopic structural degeneration and necrosis. For candida albicans, it can also suppress the transition process from spores to aggressive mycelium.

Toxicology: Long-term animal toxicity experiments have showed that ketoconazole can significantly increase the level of alkaline phosphatase and cause liver cell degeneration.

 

Packaging & Shipping

Packaging Details

25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients

Port:TIANJIN

 

 

 

Company Profile

Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its , the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.

 

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