Basic Info.
Type
Pharmaceutical Intermediates
Transport Package
According to Customer Needs
Product Description
Vonoprazan fumarate TAK-438 powder CAS 1260141-27-2 Pharmaceutical intermediates
Product Description
Product name | TAK-438 |
CAS | 1260141-27-2 |
Molecular Formula | C21H20FN3O6S |
Molecular weight | 461.4634032 |
Apperance | White powder |
purity | 99% |
1. Compared with the traditional proton pump inhibitor lansoprazole, Vonoprazan works by competitively and reversibly inhibiting K+ in the proton pump. Clinical and animal experiments have shown that Vonoprazan is more resistant to PPI or H2 receptors than PPI or H2 receptors. The onset of lag agent is faster, the effect of increasing pH is stronger, it can quickly relieve the symptoms of digestive tract, the enzyme activity recovers after dissociation, and there are few adverse reactions. The prevention and treatment of gastric and duodenal ulcers, and the eradication of Helicobacter pylori as a first-line treatment plan have significant therapeutic effects. The curative effect is higher than that of lansoprazole, and the adverse reactions are small.
2. Vonorazan has high lipophilicity and high dissociation constant. It can take effect without acid activation in an acidic environment. The inhibitory effect of vonoprazan on the proton pump does not require acid activation, enters the stomach at high concentrations, and produces the greatest inhibitory effect after the first dose, and lasts for 24 hours. Vonolazan is stable in acid, can rapidly increase the pH value in the stomach, and exert an acid-suppressing effect.
3. At the therapeutic dose, vonoprazan has little effect on other enzymes, little effect on the physiological function of the body, good safety and easier tolerability.
Detailed Photos
Company Profile
Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries. The company has a strong scientific research and technical team, can provide customers with high quality products and a full range ofservices. We will provide firstclass products and better service to face the needs of customers, to meet the challenges of the market. Welcome domestic and foreign customers to negotiate.
Packaging & Shipping
Shipping Terms |
By Express | By Air | By Sea |
Suitable for under 50kg Fast: 3-7 days Door to door service, easy to pick up the goods | Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed | Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed |
Our Advantages
1.Any inquiry or message will be replied within 12 hours.
2.Professional manufacturer. Welcome to visit our website.
3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
4.Fast delivery.
5.After-sale services
FAQ
Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.
Q2. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.
Q3. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.
Q4. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.
Q5. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.
Q6. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.
Q7. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
Q8.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.
Address:
Room1810, Future Time Zhongshan Road, Shijiazhuang, Hebei, China
Business Type:
Manufacturer/Factory
Business Range:
Agriculture & Food, Health & Medicine
Company Introduction:
Hebei Lingding Biotechnology Co., Ltd. is a professional business company, that include pharmaceutical raw materials, pharmaceutical intermediates, and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer′s serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company′s products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries. The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market. Welcome domestic and foreign customers to negotiate.