Storage Method: | Normal |
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State: | Powder |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Refined |
Colour: | White |
Samples: |
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Raw Powder Pharmaceutical Oseltamivir CAS 196618-13-0
Product Name | Oseltamivir |
CAS | 196618-13-0 |
EINECS | 1308068-626-2 |
Assay | 99% |
Appearance | White Powder |
MF | C16H28N2O4 |
What is Oseltamivir?
Oseltamivir (oseltamivir phosphate) is a neuraminidase inhibitor antiviral drugs. Oseltamivir is the first orally effective neuraminidase inhibitor drugs are effective for influenza A and B virus. Oral oseltamivir after liver and intestinal esterase rapidly catalytic conversion to its active metabolite oseltamivir carboxylate, transition oseltamivir carboxylic acid configuration and neuraminic acid similar to competing with the influenza virus neuraminidase (NA) activity of binding sites, which is a highly selective inhibitor of NA influenza virus a potent (NAIs), it is mainly through the interference of the virus from the infected host cell release, thereby reducing the spread of influenza or influenza B virus.
Application:
The configuration of oseltamivir carboxylic acid is similar to the transition state of neuraminic acid, and it can competitively bind to the active site of influenza virus neuraminidase (NA), so it is a potent and highly selective influenza Viral NA inhibitors (NAIs), which mainly interfere with the release of viruses from infected host cells, thereby reducing the spread of influenza A or B viruses.
Use of Oseltamivir
Oseltamivir is a prodrug of its active metabolite, and its active metabolite (oseltamivir carboxylate) is a selective influenza virus neuraminidase inhibitor. Neuraminidase is a glycoprotein on the surface of the virus whose activity is essential for the release of newly formed viral particles from infected cells and the further spread of infectious viruses in the human body. The active metabolite of oseltamivir phosphate inhibits the neuraminidase activity of influenza A and B viruses. The half-inhibitory concentration of viral neuraminidase activity in vitro is as low as the nanogram level. It has been observed in vitro that active metabolites inhibit the growth of influenza virus, and its inhibition of influenza virus replication and pathogenicity is also observed in vivo. This product reduces the spread of influenza A or B by inhibiting the release of the virus from infected cells. Studies of naturally acquired and laboratory influenza have shown that the use of oseltamivir phosphate does not affect the body's normal humoral immune response to infection. The antibody response to the inactivated vaccine was not affected by treatment with oseltamivir phosphate.
Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates, and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
1. who are we?
We are based in Hebei, China, start from 2021,sell to North America(30.00%),Northern Europe(15.00%),Central America(10.00%),Eastern Europe(10.00%),Western Europe(8.00%),Southern Europe(8.00%),Mid East(5.00%),South Asia(3.00%),South America(3.00%),Africa(3.00%),Domestic Market(2.00%),Oceania(2.00%),Southeast Asia(1.00%). There are total about 11-50 people in our office.
2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;
3.what can you buy from us?
Chloronicotinicacid,2 3-Dichloropyridine,Choline glycerophosphate ,Nicotinamide
4. why should you buy from us not from other suppliers?
Hebei Lingding Biotechnology Co., Ltd. has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with meticulous and though services.
5. what services can we provide?
Accepted Delivery Terms: FOB, CFR, CIF, EXW, Express Delivery;
Accepted Payment Currency: USD;
Accepted Payment Type: T/T, MoneyGram, Western Union ,Cash;
Language Spoken :English, Chinese
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