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Audited Supplier Nesiritide acetate is recombinant B-type natriuretic peptide (BNP). BNP is often clinically used as a biomarker for cardiovascular problems like ventricular failure, stroke, and myocardial infarction. Nesiritide exhibits immunosuppressive, anti-inflammatory, and cardioprotective activities. Nesiritide exhibits mixed effects when administered clinically in the treatment of heart failure. Nesiritide decreases CD8+ T cells and levels of TNF-α, IL-1α, and IL-6. This peptide inhibits angiotensin II (ATII)-induced hypertrophy in animal models. Nesiritide suppresses generation of ROS, prevents decreases in the mitochondrial membrane potential, increases levels of Bcl-2, and decreases levels of Bax, inhibiting apoptosis and protecting cardiomyocytes against ischemia/reperfusion-induced injury. The additional diuretic, natriuretic, and vasorelaxant effects of nesiritide are mediated by its binding of the natriuretic peptide receptor A (guanylate cyclase A).
| Product Name: | Nesiritide acetate |
| CAS: | 114471-18-0 |
| MF: | C143H244N50O42S4 |
| MW: | 3464.04 |
Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market. Welcome domestic and foreign customers to negotiate.
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